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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKG
All Species:
30.61
Human Site:
Y187
Identified Species:
56.11
UniProt:
P49619
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49619
NP_001074213.1
791
89096
Y187
L
E
F
M
F
R
L
Y
D
S
D
E
N
G
L
Chimpanzee
Pan troglodytes
XP_001152821
791
89168
Y187
L
E
F
M
F
R
L
Y
D
S
D
E
N
G
L
Rhesus Macaque
Macaca mulatta
XP_001092912
791
89195
Y187
L
E
F
M
F
R
L
Y
D
S
D
E
N
G
L
Dog
Lupus familis
XP_545239
790
88986
Y186
L
E
F
M
F
R
L
Y
D
S
D
E
N
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG7
788
88505
D193
S
D
E
N
G
L
L
D
Q
A
E
M
D
Q
I
Rat
Rattus norvegicus
P49620
788
88503
D187
M
F
R
L
Y
D
S
D
E
N
E
L
L
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
K147
L
G
L
E
N
N
V
K
D
D
G
Q
H
V
W
Chicken
Gallus gallus
XP_422650
933
102351
Y293
L
E
F
M
F
R
L
Y
H
T
D
G
N
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696120
893
99287
Y266
L
E
F
M
F
R
L
Y
D
T
D
G
N
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
Y298
L
E
F
M
F
R
L
Y
D
T
D
S
N
G
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
D191
S
D
G
N
G
F
L
D
K
S
E
I
D
G
I
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
Y590
L
E
F
M
F
R
L
Y
D
T
D
D
N
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
S178
Y
C
D
E
S
C
S
S
S
F
L
G
G
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
94
N.A.
89.7
88.2
N.A.
51.3
54.9
N.A.
59.2
N.A.
35.5
N.A.
46
38.3
Protein Similarity:
100
99.7
97.8
95.5
N.A.
94.1
93
N.A.
63.5
65.9
N.A.
72.7
N.A.
46.5
N.A.
63.2
48.8
P-Site Identity:
100
100
100
100
N.A.
6.6
0
N.A.
13.3
73.3
N.A.
86.6
N.A.
80
N.A.
20
80
P-Site Similarity:
100
100
100
100
N.A.
40
40
N.A.
33.3
86.6
N.A.
93.3
N.A.
93.3
N.A.
46.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
0
0
8
0
24
62
8
62
8
16
8
0
% D
% Glu:
0
62
8
16
0
0
0
0
8
0
24
31
0
0
0
% E
% Phe:
0
8
62
0
62
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
8
0
16
0
0
0
0
0
8
24
8
70
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
31
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
70
0
8
8
0
8
77
0
0
0
8
8
8
0
39
% L
% Met:
8
0
0
62
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
16
8
8
0
0
0
8
0
0
62
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
8
% Q
% Arg:
0
0
8
0
0
62
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
0
0
8
0
16
8
8
39
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
8
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _